KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO1
All Species:
33.33
Human Site:
S268
Identified Species:
56.41
UniProt:
P06733
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06733
NP_001419.1
434
47169
S268
F
K
S
P
D
D
P
S
R
Y
I
S
P
D
Q
Chimpanzee
Pan troglodytes
XP_511294
434
46968
A268
F
K
S
P
D
D
P
A
R
H
I
T
G
E
K
Rhesus Macaque
Macaca mulatta
XP_001098883
434
47136
S268
F
K
S
P
D
D
P
S
R
Y
I
S
P
D
Q
Dog
Lupus familis
XP_536606
434
47036
A268
F
K
S
P
D
D
P
A
R
H
I
T
G
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P17182
434
47122
S268
F
K
S
P
D
D
P
S
R
Y
I
T
P
D
Q
Rat
Rattus norvegicus
P04764
434
47109
S268
F
K
S
P
D
D
A
S
R
Y
I
T
P
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505468
461
50129
S268
F
K
S
P
D
D
P
S
R
Y
I
S
P
D
Q
Chicken
Gallus gallus
P51913
434
47286
S268
F
K
S
P
D
D
P
S
R
Y
I
S
P
D
Q
Frog
Xenopus laevis
P08734
434
47486
S268
F
K
S
P
D
D
P
S
R
Y
I
S
P
D
K
Zebra Danio
Brachydanio rerio
NP_997887
432
47041
S268
F
K
S
P
D
D
P
S
R
Y
I
S
P
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15007
500
54292
K335
F
K
N
E
K
S
D
K
S
Q
W
L
P
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27527
434
46598
S268
F
K
N
P
A
S
D
S
S
K
W
L
S
G
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42895
446
48144
N274
L
N
F
K
E
E
N
N
D
G
S
Q
K
I
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25696
444
47701
N273
N
F
K
E
E
N
N
N
G
S
Q
K
I
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.4
99.7
83.8
N.A.
94.6
94.6
N.A.
87.1
92.8
87.7
89.8
N.A.
63.5
N.A.
75.1
N.A.
Protein Similarity:
100
91.2
100
91.7
N.A.
98.8
98.1
N.A.
90.8
96.3
94.2
95.3
N.A.
73
N.A.
87
N.A.
P-Site Identity:
100
60
100
60
N.A.
93.3
86.6
N.A.
100
100
93.3
93.3
N.A.
20
N.A.
26.6
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
100
93.3
N.A.
100
100
100
100
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
69.9
N.A.
71.6
N.A.
N.A.
Protein Similarity:
N.A.
81.6
N.A.
82.8
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
15
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
72
72
15
0
8
0
0
0
0
58
8
% D
% Glu:
0
0
0
15
15
8
0
0
0
0
0
0
0
15
8
% E
% Phe:
86
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
0
0
15
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
72
0
8
8
0
% I
% Lys:
0
86
8
8
8
0
0
8
0
8
0
8
8
0
29
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
15
0
0
8
15
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
79
0
0
65
0
0
0
0
0
65
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
43
% Q
% Arg:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% R
% Ser:
0
0
72
0
0
15
0
65
15
8
8
43
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
29
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
58
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _